Retinoid X Receptor alpha Protein (AA 111-228)
Quick Overview for Retinoid X Receptor alpha Protein (AA 111-228) (ABIN666801)
抗原
See all Retinoid X Receptor alpha (RXRA) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 111-228
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序列
- MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE
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产品特性
- RXR-alpha( Retinoid x receptor, 111-228aa, Human) Recombinant, expressed in E.coli)
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纯化方法
- > 95% by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 7.5) containing 0.1M NaCl, 5 mM beta-Mercaptoethanol
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))
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别名
- RXR alpha/RXRA
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背景
- The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms , RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34. 9 and encodes two major isoforms (RXR alpha1, RXR alpha2). The DNA binding domain of RXR (111-228aa) was over expressed in E. coli and purified by using conventional column chromatography techniques.
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分子量
- 13.5 kDa (119aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_002948
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C
抗原
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